Once a Little Girl Lost, now Drew is a Hollywood power player.

When Drew Barrymore talks, people listen. People like Cameron Diaz and Demi Moore. And if Charlie's Angels are America's secret weapon, then Barrymore is Hollywood's -- the unstoppable 28-year-old actress not only kicks ass in Full Throttle, the star-studded sequel to the 2000 blockbuster, she also produced it and is largely responsible for bringing back Diaz and luring Moore to the fold.

"I never saw myself coming back to do a sequel," admits Diaz, who is close with costars Barrymore and Lucy Liu. "I like to work with different people, different directors, different stories. Then Drew called with a new twist on the storyline and said, 'Let's do it again!' And Drew doesn't stop until she gets what she wants. She is so enthusiastic and gives you so many good reasons to participate in her adventure that there's no way to go against it."

Barrymore, who made her screen debut at 11 months in a Puppy Chow commercial, first demonstrated her celestial spirit in Steven Spielberg's children's classic,E.T., and has continued to fascinate audiences as she exults in the highs and lows (substance abuse, familial disputes and failed romances) of her life journey.

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